Supplement of the Month-Luteolin

Luteolin- from humble sources but with surprisingly varied benefits…

This amazing substance was first isolated from the reseda luteola plant(Dyer’s mignonette or yellow weed) in 1829 by a French chemist Michel Eugene Chevreul . Modern researchers have since learned a lot about its many uses: “Luteolin, a polyphenolic plant flavonoid, has been attributed with numerous beneficial properties like anti-cancer, antioxidant, and anti-inflammatory action. Luteolin has been reported earlier to be neuroprotective in models of spinal cord injury and traumatic brain injury…” https://www.frontiersin.org/articles/10.3389/fnmol.2019.00041/full

Here’s another view of the roles luteolin can plan as an important plant medicine: “The flavone luteolin has numerous useful actions that include: anti-oxidant, anti-inflammatory, microglia inhibition, neuroprotection, and memory increase. A liposomal luteolin formulation in olive fruit extract improved attention in children with ASDs and brain “fog” in mastocytosis patients.“ https://www.frontiersin.org/research-topics/3259#articles

Expanding on this in the same article, it’s a wonder every gerontologist isn’t recommending this supplement to elderly patients who are suffering from brain fog:

“Brain “fog” is a constellation of symptoms that include reduced cognition, inability to concentrate and multitask, as well as loss of short and long term memory. Brain “fog” characterizes patients with autism spectrum disorders (ASDs), celiac disease, chronic fatigue syndrome, fibromyalgia, mastocytosis, and postural tachycardia syndrome (POTS), as well as “minimal cognitive impairment,” an early clinical presentation of Alzheimer’s disease (AD), and other neuropsychiatric disorders. Brain “fog” may be due to inflammatory molecules, including adipocytokines and histamine released from mast cells (MCs) further stimulating microglia activation, and causing focal brain inflammation.”

As you read above, applications go beyond senile brain fog including such catch-all diagnoses as CFS. Since luteolin can be easily extracted from common plant sources,i including peanut shells and inexpensively offered, it will not be promoted by the drug companies that steer the allopathic enterprise, so this supplement, if it applies to you, is one where the healthcare consumer must arm him or her self with the information and make good choices- the medical apparatu$ is looking out for the pharmaceutical companies and medical device companies and intelligent, informed self-care does not buy that third vacation home or second yacht….

PubMed cites Luteolin as a valuable ally in fighting cancer, suppressing tumors, and inducing apoptosis (normal cell death- cancer cells are “immortal” and that is part of their danger- this promotes apoptosis, whereby body gets rid of them). https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2615542/

“Luteolin’s anticancer property is associated with the induction of apoptosis, and inhibition of cell proliferation, metastasis and angiogenesis. Furthermore, luteolin sensitizes cancer cells to therapeutic-induced cytotoxicity through suppressing cell survival pathways such as phosphatidylinositol 3′-kinase (PI3K)/Akt, nuclear factor kappa B (NF-κB), and X-linked inhibitor of apoptosis protein (XIAP), and stimulating apoptosis pathways including those that induce the tumor suppressor p53. These observations suggest that luteolin could be an anticancer agent for various cancers.”

This blog cannot recommend any kind of medical choices or procedures or advise for or against anything of the sort. We’re simply sharing information about supplements that may be useful for you to know. Of course, speak with your licensed healthcare professional before taking any supplement.